Sec-Butylamine

From WikiMD's Food, Medicine & Wellness Encyclopedia

Sec-Butylamine, also known as 2-butylamine, is an organic compound with the formula CH₃CH₂CH(NH₂)CH₃. It is a secondary amine where the amino group is attached to the second carbon of a butyl chain. Sec-Butylamine is a colorless liquid at room temperature and has a strong, fishy, ammonia-like odor typical of amines. It is soluble in water and can act as a base, forming salts with acids.

Properties[edit | edit source]

Sec-Butylamine has a molecular weight of 73.14 g/mol and a boiling point of approximately 63-64°C. Its density is about 0.74 g/cm³. Being a secondary amine, it exhibits properties typical of amines, including the ability to form hydrogen bonds, which affects its solubility and boiling point.

Synthesis[edit | edit source]

Sec-Butylamine can be synthesized through several methods, including the alkylation of ammonia with butanol in the presence of a catalyst. Another common method involves the reduction of n-butyl nitrite or sec-butyl nitrite with hydrogen in the presence of a catalyst.

Applications[edit | edit source]

Sec-Butylamine is used in the synthesis of pharmaceuticals, agrochemicals, and dyes. It serves as an intermediate in the production of various compounds, including inhibitors, rubber chemicals, and surfactants. Its basic nature allows it to neutralize acids, making it useful in various industrial processes.

Safety[edit | edit source]

Handling sec-butylamine requires caution due to its flammability and the potential for skin, eye, and respiratory irritation. Proper personal protective equipment, including gloves and goggles, should be used when working with this chemical. It should be stored in a cool, well-ventilated area away from sources of ignition.

Environmental Impact[edit | edit source]

Like many amines, sec-butylamine can have adverse effects on the environment if not managed properly. It is toxic to aquatic life and can cause long-term damage to aquatic ecosystems if released in significant quantities.

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Contributors: Prab R. Tumpati, MD