2,5-dimethoxy-4-(n)-propylthiophenethylamine

2,5-Dimethoxy-4-(n)-propylthiophenethylamine, also known as 2C-T-7 for short, is a psychedelic drug and entheogen belonging to the 2C family of psychoactive drugs. It is known for its hallucinogenic effects similar to those of LSD and psilocybin. The chemical name reflects its structure; it contains a thiophene ring substituted at R4 with a propyl chain, a phenethylamine backbone, and two methoxy groups at the 2 and 5 positions of the phenyl ring.

Chemistry

2C-T-7 is a synthetic compound that belongs to a broader class of phenethylamines, which are organic compounds containing a phenyl ring bound to an amino group through an ethyl chain. The presence of a thiophene ring, a sulfur-containing heterocycle, distinguishes it from other compounds in the 2C family, contributing to its unique pharmacological properties. The methoxy groups at the 2 and 5 positions increase the compound's lipophilicity, potentially affecting its ability to cross the blood-brain barrier.

Pharmacology

The pharmacological action of 2C-T-7 is primarily through its activity as a serotonin receptor agonist, with a particular affinity for the 5-HT2A receptor. This receptor subtype is closely associated with the effects of classical psychedelics. The compound's effects on the central nervous system manifest in significant alterations in sensory perception, mood, and thought patterns. The propylthiophenethylamine structure of 2C-T-7 contributes to its potency and duration of action compared to other members of the 2C family.

Effects

Users of 2C-T-7 report a wide range of effects, including visual hallucinations, altered states of consciousness, euphoria, introspection, and in some cases, anxiety or discomfort. The onset of effects typically occurs within an hour of ingestion, with the experience lasting anywhere from 4 to 15 hours, depending on the dose and individual metabolism.

Risks and Legality

Like other synthetic psychedelics, 2C-T-7 poses risks of overdose, particularly due to its potent effects and the variability in individual responses. There have been reports of hospitalizations and fatalities associated with its use, often involving combinations with other substances. Consequently, 2C-T-7 is classified as a Schedule I controlled substance in the United States and is similarly controlled in other countries, making its manufacture, distribution, and possession illegal without authorization.

Research

Research on 2C-T-7 is limited due to its legal status, but it has been the subject of studies exploring its pharmacology, toxicology, and potential therapeutic applications. The unique properties of the thiophene ring in its structure make it of interest in the development of new psychotherapeutic agents.