4-HO-NALT

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4-HO-NALT (4-hydroxy-N-allyltryptamine) is a psychedelic tryptamine that is less commonly known in the field of pharmacology. It is a structural analog of psilocin, which is the active ingredient in psilocybin mushrooms, also known as "magic mushrooms".

Chemistry[edit | edit source]

4-HO-NALT is a tryptamine compound, which is a family of compounds that share a common basic structure and are found in a variety of natural and synthetic sources. The structure of 4-HO-NALT consists of a indole ring, attached to an amino (NH2) group via an ethyl side chain. The '4-HO' in its name refers to a hydroxy (OH) group attached at the 4 position of the indole ring, and 'NALT' refers to the N-allyltryptamine part of the molecule.

Pharmacology[edit | edit source]

The pharmacological mechanisms of 4-HO-NALT are not fully understood. As a structural analog of psilocin, it is believed to act as a serotonin receptor agonist, specifically at the 5-HT2A receptor. This is the same mechanism of action as other psychedelic tryptamines and is thought to be responsible for the psychedelic effects.

Effects[edit | edit source]

The effects of 4-HO-NALT are not well-documented due to its rarity and the lack of scientific research. However, anecdotal reports suggest that it produces effects similar to other psychedelic tryptamines, including alterations in thought, perception, and mood, as well as potential visual hallucinations.

Safety[edit | edit source]

The safety profile of 4-HO-NALT is largely unknown due to the lack of scientific research. As with all psychedelics, it is advised to use caution when ingesting this substance. Potential risks may include psychological distress, adverse physical reactions, and dangerous interactions with other substances.

Legal Status[edit | edit source]

The legal status of 4-HO-NALT varies by country and it is advised to check local laws before possession or use. In some countries, it may be considered a controlled substance due to its structural similarity to psilocin.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD