4-Methylphenethylacetylfentanyl

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4-Methylphenethylacetylfentanyl (4-MPACF) is a potent opioid analgesic drug that is an analog of fentanyl. It is a member of the fentanyl series of drugs and has been found in the illicit drug market.

Chemistry[edit | edit source]

4-Methylphenethylacetylfentanyl is a fentanyl analog, meaning it has a structure very similar to that of fentanyl. It is part of the 4-methylphenethyl series of fentanyl analogs, which also includes 4-Methylphenethylacetylfentanyl and 4-Methylphenethylacetylfentanyl. The 4-methylphenethyl group in these compounds is believed to contribute to their potent opioid activity.

Pharmacology[edit | edit source]

Like other opioids, 4-Methylphenethylacetylfentanyl acts on the mu-opioid receptor to produce its analgesic effects. It is believed to be several times more potent than fentanyl, although exact potency can vary depending on the specific analog and individual patient factors.

Effects[edit | edit source]

The effects of 4-Methylphenethylacetylfentanyl are similar to those of other opioids and include analgesia, sedation, euphoria, and respiratory depression. Because of its high potency, it carries a significant risk of overdose, especially when used by individuals without a tolerance to opioids.

Legal status[edit | edit source]

4-Methylphenethylacetylfentanyl is a controlled substance in many countries due to its potential for abuse and addiction. In the United States, it is a Schedule I controlled substance under the Controlled Substances Act.

See also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD