5F-AB-FUPPYCA
5F-AB-FUPPYCA is a synthetic cannabinoid that is derived from the cannabis plant. It is a potent agonist for the CB1 receptor, and is used in the research of cannabinoid receptor agonists. 5F-AB-FUPPYCA shares a close structural relationship with a series of designer drugs that are known as FAB-144 and FUB-144.
Chemistry[edit | edit source]
5F-AB-FUPPYCA is a synthetic cannabinoid that features a fluorobenzyl group at the 1-amino-3-methyl-1-oxobutane moiety. It is an analogue of AB-FUBINACA, which features a terminal amide group on the valine residue.
Pharmacology[edit | edit source]
5F-AB-FUPPYCA is a potent agonist for the CB1 receptor, with a Ki of 0.9 nM and an EC50 of 1.8 nM. It is selective for the CB1 receptor over the CB2 receptor, with a selectivity ratio of 80:1.
Legality[edit | edit source]
In the United States, 5F-AB-FUPPYCA is a Schedule I controlled substance. It is also controlled in China.
See also[edit | edit source]
References[edit | edit source]
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