60S ribosomal protein L41

Ideogram human chromosome 12

60S ribosomal protein L41

60S ribosomal protein L41 is a protein that in humans is encoded by the RPL41 gene. This protein is a component of the 60S subunit of the ribosome, which is essential for protein synthesis in cells. It plays a crucial role in the translation process by aiding in the assembly of the ribosome and facilitating the binding of transfer RNA (tRNA) molecules to messenger RNA (mRNA) during protein synthesis.

Structure

60S ribosomal protein L41 is a ribosomal protein that is part of the large ribosomal subunit. It is composed of a single polypeptide chain that folds into a specific three-dimensional structure. This structure allows the protein to interact with other ribosomal proteins and RNA molecules within the ribosome, contributing to the overall function of the ribosome in protein synthesis.

Function

As a component of the 60S ribosomal subunit, 60S ribosomal protein L41 plays a critical role in the translation of mRNA into protein. It helps stabilize the binding of tRNA molecules to the ribosome and promotes the formation of peptide bonds between amino acids, leading to the synthesis of new proteins. Additionally, this protein may also be involved in regulating the accuracy and efficiency of protein synthesis.

Clinical Significance

Mutations in the RPL41 gene, which encodes 60S ribosomal protein L41, have been associated with certain genetic disorders and diseases. Dysregulation of ribosomal proteins like L41 can lead to defects in protein synthesis and cellular function, potentially contributing to conditions such as cancer, developmental disorders, and other diseases.