AOD9604

AOD9604 is a synthetic peptide that has been developed for its potential benefits in the field of obesity and weight management. It is a modified form of the Growth Hormone (GH) polypeptide, specifically the C-terminus fragment of the GH molecule which is responsible for the fat-reducing effects of GH, without its negative effects.

Overview

AOD9604 is a 15-amino acid peptide that was originally developed by Metabolic Pharmaceuticals Limited, an Australian company. It is a modified fragment of the human growth hormone molecule, specifically the C-terminus part of the molecule (amino acids 177-191). This fragment has been shown to stimulate lipolysis (the breakdown of fat) and inhibit lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.

Mechanism of Action

The exact mechanism of action of AOD9604 is not fully understood. However, it is known that the peptide stimulates the Pituitary Gland to increase the production and release of growth hormone. This, in turn, stimulates the breakdown of fat (lipolysis) and inhibits the formation of new fat (lipogenesis).

Clinical Trials

AOD9604 has been tested in several clinical trials. In a double-blind, placebo-controlled clinical trial, the effects of AOD9604 on body weight and body composition were studied in obese and overweight adults. The results showed a significant reduction in body weight and body fat in the AOD9604 group compared to the placebo group.

Potential Uses

AOD9604 has potential uses in the treatment of obesity and weight management. It may also have potential in the treatment of osteoporosis, due to its ability to promote bone growth. However, more research is needed to confirm these potential uses.

Safety and Side Effects

In clinical trials, AOD9604 has been shown to be well tolerated with few side effects. The most common side effects reported were mild and included headache, nausea, and fatigue. However, as with any drug, there may be risks and side effects that are not yet known.

See Also

• Growth Hormone
• Obesity
• Weight Management
• Osteoporosis