Altropane

Altropane (also known as O-587 and IACFT) is a phenyltropane derivative that acts as a dopamine reuptake inhibitor and is used in scientific research. It is primarily used in the study of Parkinson's disease and drug addiction. Altropane is a radiopharmaceutical and is used in PET scans to identify and track the progression of Parkinson's disease.

Chemistry[edit | edit source]

Altropane is a phenyltropane derivative, which means it is a synthetic compound derived from cocaine. Unlike cocaine, however, altropane has a longer biological half-life and is less likely to be abused due to its slower onset of action.

Pharmacology[edit | edit source]

Altropane acts as a dopamine reuptake inhibitor, meaning it blocks the reuptake of dopamine by the neurons that release it. This leads to an increase in the amount of dopamine available in the brain. Dopamine is a neurotransmitter that is involved in regulating mood and reward, among other things.

Medical uses[edit | edit source]

Altropane is used in scientific research to study the role of dopamine in various diseases and conditions. It is particularly useful in the study of Parkinson's disease, a neurodegenerative disorder characterized by the death of dopamine-producing neurons. By using altropane in PET scans, researchers can visualize the distribution and density of dopamine transporters in the brain, which can help in the diagnosis and tracking of Parkinson's disease.

Altropane is also used in the study of drug addiction. Because it is a dopamine reuptake inhibitor, it can help researchers understand how drugs of abuse affect the brain's reward system.

See also[edit | edit source]

Altropane Resources
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