Ankylosing vertebral hyperostosis with tylosis

Alternate names[edit | edit source]

Familial ankylosing vertebral hyperostosis with tylosis

Definition[edit | edit source]

A rare dysostosis with predominant vertebral involvement characterized by paraspinal ligament ossification (most pronounced in the lower thoracic region), osteophytosis, marginal sacroiliac joint sclerosis, and punctate hyperkeratosis on the soles and palms. Patients may be asymptomatic or present mild to moderate back pain. There have been no further descriptions in the literature since 1969.

NIH genetic and rare disease info[edit source]

NIH info on Ankylosing vertebral hyperostosis with tylosis

Ankylosing vertebral hyperostosis with tylosis is a rare disease.

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Rare diseases - Ankylosing vertebral hyperostosis with tylosis
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Also see	Comprehensive list of genetic and rare diseases
Resources	NIH GARD, US Genetic and Rare Diseases Info Rare Disease Day Undiagnosed Diseases Network Database of rare diseases at Orphanet Rare Disease UK Rare diseases search engine