Azvudine

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Azvudine.svg

Azvudine is an antiviral drug that has been developed for the treatment of certain viral infections. It is primarily known for its activity against the human immunodeficiency virus (HIV) and the hepatitis C virus (HCV).

Mechanism of Action[edit | edit source]

Azvudine is a nucleoside analog that inhibits the replication of viral RNA. It works by incorporating itself into the viral RNA chain during replication, leading to premature termination of the RNA strand. This mechanism is similar to other nucleoside analogs used in antiviral therapy, such as zidovudine and lamivudine.

Clinical Use[edit | edit source]

Azvudine has been studied for its efficacy in treating HIV/AIDS and hepatitis C. Clinical trials have shown that it can significantly reduce viral load in patients infected with these viruses. It is often used in combination with other antiretroviral drugs to enhance its effectiveness and reduce the likelihood of resistance.

Side Effects[edit | edit source]

Common side effects of Azvudine include nausea, headache, and fatigue. More severe side effects can include liver toxicity and pancreatitis. Patients taking Azvudine are monitored regularly for these adverse effects.

Research and Development[edit | edit source]

Azvudine is still under investigation in various clinical trials to determine its full potential and safety profile. Researchers are also exploring its use in treating other viral infections beyond HIV and hepatitis C.

Regulatory Status[edit | edit source]

As of now, Azvudine has received approval for use in certain countries for the treatment of HIV and hepatitis C. However, it is not yet widely available and is subject to ongoing research and regulatory review.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD