Bivalent chromosome

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Bivalent Chromosome

A bivalent chromosome is a structure that forms during the first division of meiosis, a type of cell division that results in four daughter cells each with half the number of chromosomes of the parent cell. Bivalent chromosomes are composed of two homologous chromosomes that pair up during the prophase I stage of meiosis.

Formation[edit | edit source]

The formation of a bivalent chromosome begins during the leptotene stage of prophase I, when the chromosomes start to condense. In the subsequent zygotene stage, homologous chromosomes begin to pair up, a process known as synapsis. The paired chromosomes, now referred to as a bivalent or a tetrad, remain together through the pachytene stage, during which crossing over (exchange of genetic material) occurs. The bivalent structure is maintained until the anaphase of meiosis I, when the homologous chromosomes are pulled apart and move to opposite poles of the cell.

Function[edit | edit source]

The primary function of bivalent chromosomes is to facilitate the exchange of genetic material between homologous chromosomes, a process known as crossing over. This genetic recombination results in new combinations of genes in the daughter cells, contributing to genetic diversity.

Importance in Genetics[edit | edit source]

Bivalent chromosomes play a crucial role in genetics and evolution. The process of crossing over during meiosis leads to the production of genetically unique gametes, which is a key factor in evolution. Furthermore, errors in the formation or separation of bivalent chromosomes can lead to genetic disorders such as Down syndrome and Klinefelter syndrome.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD