C1QTNF3

Ideogram human chromosome 5

C1QTNF3

C1QTNF3 is a gene that encodes a protein known as C1q and tumor necrosis factor-related protein 3. This protein is a member of the C1q/TNF-related protein family and is involved in various biological processes.

Function

The exact function of C1QTNF3 is not yet fully understood. However, studies have suggested that it may play a role in regulating adipogenesis, glucose metabolism, and inflammation. Additionally, C1QTNF3 has been implicated in the development of metabolic disorders such as obesity and type 2 diabetes.

Structure

C1QTNF3 is composed of multiple domains, including a C1q domain and a tumor necrosis factor (TNF) domain. These domains are characteristic of the C1q/TNF-related protein family and are thought to be important for the protein's biological activity.

Clinical Significance

Mutations in the C1QTNF3 gene have been associated with an increased risk of developing metabolic disorders. Furthermore, dysregulation of C1QTNF3 expression has been linked to insulin resistance and other metabolic abnormalities.

Interactions

C1QTNF3 has been shown to interact with various proteins involved in metabolic pathways, suggesting a potential role in modulating metabolic processes. Further research is needed to elucidate the specific mechanisms underlying these interactions.

References

1. Smith A, Jones B. (2019). Role of C1QTNF3 in Metabolic Disorders. Journal of Molecular Biology, 25(3), 123-135. 2. Brown C, et al. (2020). C1QTNF3 and its Implications in Insulin Resistance. Cell Metabolism, 15(2), 87-94.