CDC2L1

Ideogram human chromosome 1

CDC2L1
Identifiers
Symbol	CDC2L1
NCBI gene	983
HGNC	1721
OMIM	116947
RefSeq	NM_001786
UniProt	P30281
Other data
Locus	Chr. 1 q21
Search for Structures Swiss-model Domains InterPro

CDC2L1 is a gene that encodes the cell division cycle 2-like protein 1. This protein is involved in cell cycle regulation and plays a crucial role in cell division processes.

Function

CDC2L1 is a member of the cyclin-dependent kinase family and is closely related to the cell cycle regulator CDC2. It functions as a serine/threonine protein kinase and is involved in the regulation of cell cycle progression.

Structure

The CDC2L1 protein consists of several domains, including a kinase domain that is responsible for its enzymatic activity. It interacts with various other proteins to regulate cell division and proliferation.

Clinical Significance

Mutations in the CDC2L1 gene have been associated with certain types of cancer, highlighting its importance in maintaining proper cell cycle control. Further research is needed to fully understand the implications of CDC2L1 dysregulation in disease.

Interactions

CDC2L1 has been shown to interact with several other proteins involved in cell cycle regulation, such as cyclins and cyclin-dependent kinases. These interactions are essential for coordinating the complex processes of cell division.