Cardiac Branches Of The Vagus Nerve

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Cardiac Branches of the Vagus Nerve

The cardiac branches of the vagus nerve are critical components of the autonomic nervous system, specifically the parasympathetic division, that innervate the heart. These branches play a pivotal role in regulating heart rate and maintaining cardiovascular homeostasis. The vagus nerve, also known as the tenth cranial nerve (CN X), extends from the brainstem to the abdomen, supplying various organs, including the heart, with parasympathetic fibers.

Anatomy[edit | edit source]

The vagus nerve gives rise to several cardiac branches at different levels of its course. These branches can be categorized into the superior, middle, and inferior cardiac branches.

Superior Cardiac Branches[edit | edit source]

The superior cardiac branches arise from the cervical portion of the vagus nerve. They descend to innervate the atria, particularly affecting the sinoatrial (SA) node, which is responsible for initiating the heartbeat.

Middle Cardiac Branches[edit | edit source]

The middle cardiac branches, fewer in number, emerge from the vagus nerve at the root of the neck. They contribute to the innervation of the atrioventricular (AV) node, playing a role in heart rate regulation by influencing the conduction speed between the atria and ventricles.

Inferior Cardiac Branches[edit | edit source]

Inferior cardiac branches originate from the thoracic part of the vagus nerve. These branches primarily innervate the ventricles, although their influence on ventricular function is less pronounced compared to their effects on the atria.

Function[edit | edit source]

The cardiac branches of the vagus nerve exert their effects by releasing the neurotransmitter acetylcholine, which binds to muscarinic receptors on the heart. This binding induces a decrease in heart rate (bradycardia), reduces the force of cardiac contractions, and slows the conduction of electrical impulses through the AV node. These effects collectively contribute to the parasympathetic nervous system's role in conserving energy and promoting relaxation.

Clinical Significance[edit | edit source]

      1. Heart Rate Regulation

The cardiac branches of the vagus nerve are integral to the modulation of heart rate. Excessive vagal activity can lead to conditions such as bradycardia, while insufficient activity can result in tachycardia.

      1. Vasovagal Syncope

Overstimulation of the vagus nerve can cause vasovagal syncope, a sudden drop in heart rate and blood pressure leading to fainting. This condition often occurs in response to stress or pain.

      1. Cardiac Reflexes

The vagus nerve is involved in various cardiac reflexes, such as the Bainbridge and Bezold-Jarisch reflexes, which help regulate blood pressure and heart rate in response to changes in blood volume and chemical stimuli.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD