Clenbuterol

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Clenbuterol

Clenbuterol is a sympathomimetic amine used by sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this drug to make breathing easier. However, clenbuterol is also known for its off-label use as a weight-loss drug, similar to the use of other adrenergic agonists. It is not approved for human use in many countries, including the United States, due to its potential for adverse health effects.

Medical Uses[edit | edit source]

Clenbuterol is primarily prescribed for the treatment of obstructive pulmonary disease and other breathing disorders that require the widening of airways. Its action as a bronchodilator relaxes the muscles around airways to facilitate breathing.

Mechanism of Action[edit | edit source]

Clenbuterol works by stimulating the beta-2 receptors in the body, which leads to various effects including the widening of airways and an increase in metabolic rate. This stimulation results in an increase in body temperature and heart rate, leading to more calories being burned. This mechanism is what makes clenbuterol attractive for weight loss purposes.

Side Effects[edit | edit source]

The use of clenbuterol can lead to several side effects due to its stimulatory effects. Common side effects include headaches, tremors, and increased heart rate. More severe side effects may include heart palpitations, significant blood pressure increases, and even the potential for cardiac hypertrophy (enlargement of heart chambers) with long-term use.

Legal Status[edit | edit source]

The legal status of clenbuterol varies by country. In many countries, it is banned for all uses except for treating asthma in animals. Its use in livestock has also been a concern, as it can lead to clenbuterol residues in meat, which can affect humans consuming the meat.

Use in Sports and Fitness[edit | edit source]

Clenbuterol has been used by athletes and bodybuilders for its ability to promote fat loss while preserving muscle mass. However, its use is banned by most major sports organizations due to its performance-enhancing effects and potential health risks.

Controversies[edit | edit source]

The use of clenbuterol in livestock farming has led to numerous health incidents around the world, where people have been poisoned by consuming meat contaminated with clenbuterol. This has led to stricter regulations on its use in animals intended for food production.


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Contributors: Prab R. Tumpati, MD