Clone (B-cell)

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Clone (B-cell)

A Clone (B-cell) is a group of identical B cells that are the progeny of a single B cell. They can produce identical antibodies in response to exposure to a specific antigen.

Overview[edit | edit source]

B cells, also known as B lymphocytes, are a type of white blood cell that plays a significant role in the immune system. They are responsible for producing antibodies that can bind to harmful foreign particles such as bacteria and viruses to neutralize them. When a B cell encounters its triggering antigen, it gives rise to multiple clones of cells, some of which differentiate into plasma cells that produce antibody molecules.

Clonal Selection[edit | edit source]

The process of clonal selection begins when a B cell encounters an antigen that binds to its specific B cell receptor. This binding event triggers the B cell to divide and differentiate into a clone of identical cells. Some of these cells become plasma cells, which are the antibody factories of the immune system. Others become memory B cells, which can respond more quickly and effectively to future encounters with the same antigen.

Clonal Expansion[edit | edit source]

Clonal expansion is the rapid multiplication of B cell clones after activation by an antigen. This process is crucial for the immune response, as it allows for the production of a large number of effector cells in a short period of time. The antibodies produced by these effector cells can then neutralize the antigen, preventing it from causing harm to the body.

See Also[edit | edit source]

References[edit | edit source]


Clone (B-cell) Resources
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Contributors: Prab R. Tumpati, MD