Cocaine reverse ester

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Cocaine reverse ester is a synthetic derivative of cocaine, a powerful stimulant drug. This compound is of interest in the field of medicinal chemistry due to its potential applications in pharmacology and drug design.

Chemical Structure[edit | edit source]

The chemical structure of cocaine reverse ester is characterized by the inversion of the ester linkage present in the parent molecule, cocaine. In cocaine, the ester linkage is between the benzoyl group and the tropane ring. In cocaine reverse ester, this linkage is reversed, altering the compound's pharmacokinetics and pharmacodynamics.

Synthesis[edit | edit source]

The synthesis of cocaine reverse ester involves several steps, starting from the basic tropane structure. The process typically includes:

  • Formation of the tropane ring
  • Introduction of the benzoyl group
  • Reversal of the ester linkage

Pharmacological Properties[edit | edit source]

Cocaine reverse ester exhibits different pharmacological properties compared to cocaine. It interacts with the dopamine transporter (DAT) and other neurotransmitter systems in a unique manner, which may result in altered psychoactive effects and potential therapeutic applications.

Potential Applications[edit | edit source]

Research into cocaine reverse ester is ongoing, with potential applications including:

Safety and Toxicity[edit | edit source]

As with many synthetic derivatives, the safety and toxicity profile of cocaine reverse ester is not fully understood. Further toxicological studies are required to determine its safety for potential therapeutic use.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD