Connecting tubule

Connecting Tubule

The Connecting Tubule (also known as Cortical Collecting Duct) is a part of the nephron in the kidneys that plays a crucial role in the body's urine formation and water balance. It is the final segment of the nephron where the fine-tuning of urine concentration takes place.

Diagram of a nephron, the functional unit of the kidney. The connecting tubule is labeled as the cortical collecting duct.

Structure

The connecting tubule is a tube-like structure that connects the distal convoluted tubule to the collecting duct system. It is lined with a single layer of epithelial cells, which vary in structure and function along the length of the tubule.

Function

The primary function of the connecting tubule is to carry urine from the distal convoluted tubule to the collecting duct system. It also plays a significant role in the regulation of sodium, potassium, and acid-base balance in the body. The connecting tubule is responsive to antidiuretic hormone (ADH), which regulates water reabsorption.

Clinical Significance

Abnormalities in the connecting tubule can lead to various kidney disorders, including diabetes insipidus, hypertension, and renal tubular acidosis. Understanding the function and regulation of the connecting tubule can help in the development of treatments for these conditions.

See Also

• Nephron
• Kidney
• Distal convoluted tubule
• Collecting duct system