Ddc
Ddc - a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zalcitabine preferentially inhibits the gamma form of dna polymerase present in tumor cell mitochondria, resulting in the inhibition of tumor cell mitochondrial dna replication and tumor cell death.
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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Ddc for any updates.
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