Directly observed therapy

From WikiMD's Food, Medicine & Wellness Encyclopedia

Directly Observed Therapy (DOT) is a method of drug administration used in the treatment of chronic illnesses, including tuberculosis, HIV/AIDS, and hepatitis C. This approach involves healthcare professionals directly observing patients as they take their medication, ensuring that the treatment regimen is followed correctly.

History[edit | edit source]

The concept of Directly Observed Therapy originated in the 1950s, when it was used to manage tuberculosis (TB) patients. The World Health Organization (WHO) later adopted this strategy in its global TB control strategy, known as the "DOTS" strategy (Directly Observed Treatment, Short-course).

Methodology[edit | edit source]

In Directly Observed Therapy, a healthcare provider or trained health worker watches the patient swallow each dose of medication. This can be done in a clinic, at the patient's home, or through video technology. The goal is to ensure that the patient takes the medication exactly as prescribed, thereby improving treatment outcomes and reducing the risk of drug resistance.

Benefits[edit | edit source]

Directly Observed Therapy has several benefits. It ensures patient adherence to treatment, which is particularly important in diseases like tuberculosis where non-adherence can lead to drug resistance. It also allows for early identification and management of side effects, and provides an opportunity for patient education and support.

Criticisms[edit | edit source]

Despite its benefits, Directly Observed Therapy has been criticized for being paternalistic and infringing on patient autonomy. It can also be resource-intensive, requiring significant time and effort from healthcare providers.

Applications[edit | edit source]

While originally developed for tuberculosis, Directly Observed Therapy has been applied to other diseases, including HIV/AIDS and hepatitis C. It is also used in the treatment of some mental health conditions, such as schizophrenia and bipolar disorder, where medication adherence is crucial.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD