Extra-embryonic coelom

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Extra-Embryonic Coelom is a significant structure that forms during the early stages of embryogenesis. It is a fluid-filled cavity that separates the chorion from the amnion and yolk sac, and plays a crucial role in the development of the embryo.

Formation[edit | edit source]

The extra-embryonic coelom forms during the second week of embryogenesis. It begins as small, isolated cavities within the extra-embryonic mesoderm. These cavities gradually merge to form a single, large cavity known as the extra-embryonic coelom.

Function[edit | edit source]

The extra-embryonic coelom serves several important functions during embryogenesis. It provides a protective cushion for the developing embryo, and allows for the expansion and movement of the amniotic sac and yolk sac. It also plays a role in the formation of the umbilical cord and placenta, which are essential for the exchange of nutrients and waste products between the mother and the embryo.

Clinical Significance[edit | edit source]

Abnormalities in the formation or function of the extra-embryonic coelom can lead to a variety of congenital anomalies. These can include ectopic pregnancy, in which the embryo implants outside the uterus, and hydrops fetalis, a condition characterized by an abnormal accumulation of fluid in the fetus.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD