FITM2

From WikiMD's Food, Medicine & Wellness Encyclopedia

FITM2 (Fat Storage Inducing Transmembrane Protein 2) is a protein that in humans is encoded by the FITM2 gene. It is involved in the process of lipid droplet formation, which is crucial for the storage of triglycerides and cholesterol esters in cells.

Function[edit | edit source]

FITM2 is a member of the FITM family of proteins, which are involved in the formation of lipid droplets. These droplets are essential for the storage of triglycerides and cholesterol esters in cells. The FITM2 protein is primarily located in the endoplasmic reticulum, where it plays a key role in the initial stages of lipid droplet formation.

Clinical significance[edit | edit source]

Mutations in the FITM2 gene have been associated with various metabolic disorders, including obesity and type 2 diabetes. Further research is needed to fully understand the role of FITM2 in these conditions.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD