Freeze-dried

Freeze-drying is a complex process of preserving a substance by rapidly freezing it and then extracting the frozen water under a vacuum, particularly as a means of preserving food or biological material. The process is also known as lyophilization or cryodesiccation.

Process

The freeze-drying process consists of three stages: pre-freezing, primary drying, and secondary drying.

Pre-freezing

The material is cooled below its triple point, the lowest temperature at which the solid and liquid phases of the material can coexist. This ensures that sublimation rather than melting will occur in the following steps.

Primary Drying

During the primary drying phase, the pressure is lowered (to the point of a vacuum) and enough heat is supplied to the material for the water to sublimate. The amount of heat necessary can be calculated using the sublimating molecules’ latent heat of sublimation.

Secondary Drying

In the secondary drying phase, the pressure is lowered to remove the water molecules that are adsorbed by the solid material.

Applications

Freeze-drying is used in a variety of sectors, including the pharmaceutical industry, in food preservation, and in the restoration of water-damaged documents and books.

Pharmaceutical Industry

In the pharmaceutical industry, freeze-drying is used to preserve biological materials that are unstable in their liquid form, such as vaccines and other injectables.

Food Preservation

In food preservation, freeze-drying is used to preserve a wide variety of foods, including fruits, vegetables, meats, and dairy products. The process retains the nutritional content of the food, while removing the water content that bacteria, yeasts, and molds need to grow.

Document Restoration

Freeze-drying is also used in the restoration of water-damaged documents and books. The process can effectively remove water and reduce swelling without causing further damage to the paper.

Advantages and Disadvantages

Freeze-drying has several advantages over other preservation methods. However, it also has some disadvantages.

Advantages

• It maintains the original structure and preserves the nutritional content of the food.
• It allows for long-term storage at room temperature.
• It reduces the weight of the product, which can lower transportation costs.

Disadvantages

• It is a slow and energy-intensive process.
• It requires expensive equipment and high operating costs.
• The texture of the rehydrated product may be different from the original.

See Also

• Dehydration
• Food preservation
• Pharmaceutical industry

Freeze-dried Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski