Gtp binding protein 2

Gtp binding protein 2 (also known as GTPBP2) is a protein that in humans is encoded by the GTPBP2 gene. This protein is part of the larger family of GTP-binding proteins, which play a crucial role in numerous cellular processes.

Function

GTPBP2 is a member of the MMR1/HSR1 GTP-binding protein family. It is a GTPase, an enzyme that hydrolyzes GTP to GDP (Guanosine diphosphate). This hydrolysis process is important for the regulation of a variety of cellular processes, including protein synthesis, cell division, and signal transduction.

Structure

The GTPBP2 protein is composed of several domains, including a GTP-binding domain, which is responsible for binding to GTP, and a helical domain, which is involved in protein-protein interactions. The exact structure of GTPBP2 is still under investigation, but it is known to be a large protein, with a molecular weight of approximately 100 kDa.

Clinical significance

Mutations in the GTPBP2 gene have been associated with a variety of diseases, including neurodegenerative diseases and certain types of cancer. Further research is needed to fully understand the role of GTPBP2 in these diseases.

See also

• GTP-binding protein
• GTPase
• Guanosine triphosphate

External links

• GTPBP2 at the National Center for Biotechnology Information

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