Guanoxan

Guanoxan is a sympatholytic drug that was formerly used in the treatment of hypertension. It functions by inhibiting the sympathetic nervous system, which plays a key role in the body's fight or flight response. Guanoxan is no longer commonly used due to the development of newer drugs with fewer side effects.

Mechanism of Action

Guanoxan works by blocking the adrenergic receptor, specifically the alpha-1 subtype. This results in a decrease in vasoconstriction, which in turn lowers blood pressure. The drug also has some effect on the alpha-2 receptor, but this is less significant.

Side Effects

Like all drugs, Guanoxan can cause side effects. These may include dizziness, headache, and nausea. In rare cases, it can cause more serious side effects such as arrhythmia or hypotension.

History

Guanoxan was first synthesized in the 1960s and was widely used for several decades. However, it has largely been replaced by newer drugs that are more effective and have fewer side effects.

See Also

• Sympatholytic
• Hypertension
• Adrenergic receptor

Guanoxan Resources
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