Homofentanyl

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Homofentanyl


Homofentanyl is a potent synthetic opioid that belongs to the fentanyl family of drugs. It is a designer drug that is often used illicitly for its strong analgesic effects.

History[edit | edit source]

Homofentanyl was first synthesized in the late 20th century as part of a series of fentanyl analogues. It was developed in a laboratory setting and was not initially intended for human consumption. However, it has since found its way onto the illicit drug market.

Pharmacology[edit | edit source]

Like other opioids, homofentanyl works by binding to the mu-opioid receptor in the brain. This binding action results in a decrease in the perception of pain, as well as feelings of euphoria. However, homofentanyl is significantly more potent than many other opioids, including morphine. This high potency increases the risk of overdose and makes homofentanyl a particularly dangerous drug.

Legal Status[edit | edit source]

In many countries, including the United States, homofentanyl is classified as a Schedule I drug. This means that it is illegal to manufacture, distribute, or possess the drug. Despite this, homofentanyl continues to be available on the illicit drug market.

Health Risks[edit | edit source]

The use of homofentanyl carries significant health risks. These include respiratory depression, which can lead to death, as well as dependence and addiction. Long-term use can also result in a range of physical and mental health problems, including liver damage and mental health disorders.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD