Influenza pandemics

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Influenza Pandemics

Influenza pandemics are global outbreaks of influenza caused by a new strain of the influenza virus that is capable of spreading easily from person to person. Unlike the more common seasonal outbreaks of influenza, pandemics occur irregularly, with the 20th and 21st centuries witnessing four major influenza pandemics: the 1918 influenza pandemic (Spanish flu), the 1957 influenza pandemic (Asian flu), the 1968 influenza pandemic (Hong Kong flu), and the 2009 influenza pandemic (H1N1 or swine flu).

Causes and Spread[edit | edit source]

Influenza pandemics arise due to a process known as antigenic shift, a sudden change in the influenza virus that results in a new subtype of the virus. This change can occur when two different strains of the virus infect the same cell and exchange genetic material. Because people have little to no immune protection against the new subtype, it can spread rapidly among humans.

The spread of influenza is facilitated through respiratory droplets when infected individuals cough, sneeze, or talk. It can also spread by touching surfaces contaminated with the virus and then touching the mouth, nose, or eyes.

Historical Pandemics[edit | edit source]

1918 Influenza Pandemic[edit | edit source]

The 1918 influenza pandemic, also known as the Spanish flu, was the deadliest in history, infecting an estimated one-third of the world's population and causing the deaths of approximately 50 million people. It was caused by an H1N1 virus with genes of avian origin.

1957 Influenza Pandemic[edit | edit source]

The 1957 influenza pandemic, or Asian flu, was caused by an H2N2 virus. It originated in East Asia, spreading to countries worldwide and resulting in approximately 1-2 million deaths.

1968 Influenza Pandemic[edit | edit source]

The 1968 influenza pandemic, known as the Hong Kong flu, was caused by an H3N2 virus. It resulted in approximately one million deaths worldwide.

2009 Influenza Pandemic[edit | edit source]

The most recent pandemic, the 2009 influenza pandemic, was caused by an H1N1 virus. It was first identified in the United States and spread quickly across the globe. The World Health Organization declared the pandemic over in August 2010, but the H1N1 virus continues to circulate as a seasonal flu virus.

Prevention and Control[edit | edit source]

Prevention and control measures for influenza pandemics include vaccination, antiviral drugs, personal protective measures (such as hand hygiene and wearing masks), and public health measures (such as school closures and restrictions on public gatherings). The development and distribution of vaccines are crucial in controlling the spread of the virus.

Impact[edit | edit source]

Influenza pandemics can have a significant impact on society, causing widespread illness, death, and economic disruption. The healthcare system can become overwhelmed, and there can be a significant impact on global trade and travel.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD