Islet cell adenomatosis

Islet cell adenomatosis is a rare endocrine disorder characterized by the development of multiple adenomas in the islet cells of the pancreas. This condition is often associated with hyperinsulinism, which leads to an overproduction of insulin and subsequent hypoglycemia.

Etiology

The exact cause of islet cell adenomatosis is unknown. However, it is believed to be associated with certain genetic mutations. Some researchers suggest that it may be an autosomal dominant condition, meaning that only one copy of the altered gene is necessary for the disorder to develop.

Symptoms

The symptoms of islet cell adenomatosis are primarily related to the overproduction of insulin. These may include hypoglycemia, weight gain, blurred vision, fatigue, and irritability. In severe cases, it can lead to seizures and loss of consciousness.

Diagnosis

Diagnosis of islet cell adenomatosis is typically made through a combination of clinical examination, blood tests, and imaging studies. Magnetic resonance imaging (MRI) or computed tomography (CT) scans may be used to identify the presence of adenomas in the pancreas.

Treatment

Treatment for islet cell adenomatosis primarily involves managing the symptoms of hyperinsulinism. This may include dietary modifications, medications to reduce insulin production, and in severe cases, surgical removal of the adenomas or a portion of the pancreas.

Prognosis

The prognosis for individuals with islet cell adenomatosis varies depending on the severity of the condition and the individual's response to treatment. With appropriate management, many individuals can lead normal, healthy lives.

See also

• Pancreatic disease
• Endocrine disease
• Adenoma
• Hyperinsulinism

This <a href="/wiki/Rare_disease" title="Rare disease">rare disease</a>-related article is a <a href="/wiki/Stub" title="Stub">stub</a>. You can help <a href="/wiki/WikiMD" title="WikiMD">WikiMD</a> by expanding it.