Metubine iodide

Metubine Iodide is a pharmacological agent that belongs to the class of non-depolarizing neuromuscular-blocking drugs. It is primarily used in anesthesia to induce muscle relaxation during surgery.

Pharmacology

Metubine Iodide works by blocking the action of acetylcholine, a neurotransmitter that transmits signals in the nervous system. By inhibiting the action of acetylcholine at the neuromuscular junction, Metubine Iodide causes muscle relaxation.

Clinical Use

In the field of anesthesiology, Metubine Iodide is used to relax the muscles during surgical procedures. This muscle relaxation allows surgeons to perform operations with less physical resistance from the patient's body. It is also used in certain diagnostic tests to assess the health of the neuromuscular system.

Side Effects

Like all medications, Metubine Iodide can cause side effects. These may include hypotension, tachycardia, and bronchospasm. In rare cases, it can cause an allergic reaction known as anaphylaxis.

History

Metubine Iodide was first synthesized in the mid-20th century as part of a series of compounds designed to mimic the action of curare, a poison used by indigenous peoples in South America to paralyze their prey.

See Also

• Neuromuscular-blocking drug
• Anesthesia
• Acetylcholine