Million Women Study

Million Women Study is a clinical study that was initiated in the United Kingdom in 1996. The study was designed to investigate the effects of specific types of hormone replacement therapy (HRT) on the health of women. The study is one of the largest studies of women's health, involving more than one million women aged 50 and over.

Background

The Million Women Study was initiated by the Cancer Epidemiology Unit at the University of Oxford. The study was designed to investigate the effects of specific types of HRT on the health of women, particularly in relation to breast cancer. The study also investigates other aspects of women's health, including the use of contraceptives, diet, and lifestyle factors.

Methodology

Women aged 50 and over were recruited through National Health Service breast screening clinics in the UK. Participants completed a questionnaire about their health and lifestyle, and have been followed up every three to five years with additional questionnaires. The study also uses data from national registries of hospital admissions and deaths.

Findings

The Million Women Study has produced a number of significant findings. It has shown that certain types of HRT increase the risk of breast cancer, and that this risk increases with duration of use. The study has also shown that the risk decreases after HRT is stopped. Other findings relate to the effects of HRT on the risk of stroke and endometrial cancer.

Impact

The findings of the Million Women Study have had a significant impact on the use of HRT. The study has led to changes in guidelines for the use of HRT, with a greater emphasis on the risks as well as the benefits. The study has also contributed to a decrease in the use of HRT.

See also

• Women's health
• Epidemiology
• Breast cancer
• Hormone replacement therapy

External links

• Official website

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