Nonbenzodiazepines

Nonbenzodiazepines are a class of psychoactive drugs that are very similar to benzodiazepines, but have distinct differences in terms of chemical structure and mechanism of action. They are used primarily as sleeping aids, and are also used in the treatment of certain anxiety disorders.

History

Nonbenzodiazepines were first introduced in the 1980s as an alternative to benzodiazepines, which were associated with a number of side effects and potential for addiction. The first nonbenzodiazepine to be developed was zopiclone, which was introduced in 1986.

Pharmacology

Nonbenzodiazepines act on the same GABA receptors as benzodiazepines, but they bind to a different site on the receptor. This results in a similar effect to benzodiazepines, but with fewer side effects and a lower risk of addiction.

Uses

Nonbenzodiazepines are primarily used as sleeping aids, particularly in the treatment of insomnia. They are also used in the treatment of certain anxiety disorders, although they are not as commonly used for this purpose as benzodiazepines.

Side effects

The side effects of nonbenzodiazepines are generally less severe than those of benzodiazepines, but can still include drowsiness, dizziness, and impaired coordination. There is also a risk of tolerance and withdrawal symptoms if the drug is used for a long period of time.

See also

• Benzodiazepines
• Z-drugs
• GABA receptor

Nonbenzodiazepines Resources
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