OR2L8

OR2L8 is a gene that encodes a protein in humans. This protein is part of the olfactory receptor family, a group of proteins that are involved in the detection of smell. The OR2L8 gene is located on chromosome 1, specifically at 1q44.

Function

The protein encoded by the OR2L8 gene is an olfactory receptor. Olfactory receptors are part of a large family of G-protein coupled receptors (GPCR) that are involved in the detection of odors. These receptors are located in the olfactory epithelium, a specialized tissue in the nose that is responsible for smell. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive the smell.

Structure

The OR2L8 protein is a transmembrane protein, meaning it spans the membrane of the cell. Like other GPCRs, it has seven transmembrane domains. These domains are regions of the protein that span the cell membrane, allowing the protein to receive signals from outside the cell and transmit them inside the cell.

Clinical significance

While the specific role of OR2L8 in disease is not well understood, olfactory receptors in general have been implicated in a variety of diseases, including Parkinson's disease, Alzheimer's disease, and certain types of cancer. Further research is needed to understand the specific role of OR2L8 in these and other diseases.

See also

• Olfactory receptor
• G protein-coupled receptor
• Olfactory epithelium

References

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