OR4D10

OR4D10 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are involved in the detection of smell. The OR4D10 gene is specifically expressed in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell.

Structure

The OR4D10 gene is located on chromosome 7 in humans. It spans approximately 1 kilobase and consists of a single exon. The encoded protein is a member of the class A rhodopsin-like family of G protein-coupled receptors. It is composed of 312 amino acids and has a predicted molecular weight of approximately 35 kilodaltons.

Function

The OR4D10 protein is a member of the olfactory receptor family, which is responsible for the detection of odorant molecules in the nose. These receptors are activated by specific odorant molecules, leading to a signal transduction pathway that results in the perception of smell. The specific function of OR4D10 is not well understood, but it is thought to play a role in the detection of certain smells.

Clinical significance

Mutations in the OR4D10 gene have been associated with a reduced ability to smell, a condition known as anosmia. However, the exact role of OR4D10 in this condition is not well understood.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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