OR5T2

From WikiMD's Food, Medicine & Wellness Encyclopedia

OR5T2 is a gene that encodes a protein in humans. This protein is a member of the olfactory receptor family, a class of G protein-coupled receptors which are involved in the detection of smell. The OR5T2 gene is located on chromosome 11.

Function[edit | edit source]

The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Clinical significance[edit | edit source]

While the specific function of OR5T2 is not fully understood, it is believed to play a role in the detection of smell. Mutations in this gene could potentially lead to a reduced sense of smell, or anosmia. Further research is needed to fully understand the clinical significance of this gene.

See also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD