OR6C2

OR6C2 is a gene that encodes a protein in humans. It is also known as the olfactory receptor, family 6, subfamily C, member 2. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.

Function

The OR6C2 gene provides instructions for making a protein that is involved in the detection of smell (olfaction). This protein is a member of a large family of proteins called olfactory receptors, which are located on the surface of cells in the nose. These receptors detect inhaled chemicals, leading to a signal being sent to the brain and the perception of a smell.

Structure

The OR6C2 gene is located on the short (p) arm of chromosome 11 at position 15. The exact sequence of the OR6C2 gene is a string of DNA nucleotides which encodes the production of the OR6C2 protein. This protein is embedded in the cell membrane of olfactory receptor neurons in the nose, where it binds to specific odorant molecules and triggers a signal transduction pathway.

Clinical significance

Mutations in the OR6C2 gene can lead to a reduced ability to smell, a condition known as anosmia. This can be either specific to certain smells or more general. Further research is needed to fully understand the role of OR6C2 in human health and disease.

See also

• Olfactory receptor
• Anosmia
• Chromosome 11 (human)

References

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