OR7G2

OR7G2 is a gene that encodes a protein in humans. This protein is part of the olfactory receptor family, a group of proteins that are involved in the detection of smell. The OR7G2 gene is located on chromosome 17.

Function

The olfactory receptor proteins, such as the one encoded by the OR7G2 gene, are located in the cell membranes of olfactory receptor neurons in the nose. These proteins bind to odor molecules, triggering a nerve impulse that is sent to the brain. This process allows us to detect and identify different smells.

Structure

The OR7G2 protein is a member of the G protein-coupled receptor (GPCR) superfamily. Like other GPCRs, it has seven transmembrane domains, which span the cell membrane. The protein also has an extracellular N-terminus and an intracellular C-terminus.

Clinical significance

While the exact role of the OR7G2 gene in disease is not well understood, mutations in olfactory receptor genes have been linked to a variety of disorders, including anosmia (the inability to smell), and hyposmia (reduced ability to smell).

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia
• Hyposmia

References

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