Pipotiazine palmitate

Pipotiazine Palmitate is a typical antipsychotic drug of the phenothiazine class. It was introduced in the 1960s by Rhône-Poulenc and is used in the treatment of schizophrenia. It is a long-acting injectable antipsychotic also known as a depot injection used for maintenance therapy in patients with schizophrenia and other related psychotic disorders.

Pharmacology

Pipotiazine Palmitate is a dopamine antagonist with anticholinergic and sedative properties. It works by blocking the action of dopamine, a neurotransmitter in the brain that neurons use to communicate with each other. By blocking the action of dopamine, Pipotiazine Palmitate helps to control the symptoms of schizophrenia and other psychotic disorders.

Clinical Use

Pipotiazine Palmitate is used in the treatment of chronic schizophrenia and other related psychotic disorders. It is particularly useful in patients who are non-compliant with their medication, as the long-acting injectable form allows for less frequent dosing and ensures that the patient receives their medication.

Side Effects

Like all antipsychotic drugs, Pipotiazine Palmitate has potential side effects. These can include extrapyramidal symptoms such as tremors, rigidity, and akathisia, anticholinergic effects such as dry mouth and blurred vision, and sedation. Rare but serious side effects can include tardive dyskinesia, a condition characterized by involuntary movements, and neuroleptic malignant syndrome, a potentially life-threatening reaction to antipsychotic drugs.

See Also

• Phenothiazine
• Antipsychotic
• Schizophrenia
• Depot injection

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