Proligestone

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Proligestone is a synthetic, steroidal progestin that is used in veterinary medicine to control estrus in animals. It is not used in humans. Proligestone is marketed under the brand name Delvosteron.

Pharmacology[edit | edit source]

Proligestone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has strong progestogenic effects and no other important hormonal activity.

Chemistry[edit | edit source]

Proligestone, also known as 17α-acetoxy-6-chloropregna-4,6-diene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone. It is more specifically a derivative of 17α-hydroxyprogesterone and is a member of the gonane (18-gonane) group of progestins.

History[edit | edit source]

Proligestone was introduced for veterinary use in the 1970s.

Society and culture[edit | edit source]

Proligestone is marketed for veterinary use under the brand name Delvosteron.

See also[edit | edit source]

Proligestone Resources
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Contributors: Prab R. Tumpati, MD