SLC22A18
SLC22A18 is a gene that in humans is encoded by the SLC22A18 protein. It is also known as the solute carrier family 22 member 18 gene. This gene is located on chromosome 11p15.5, a region which is associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, and lung cancer.
Function[edit | edit source]
The SLC22A18 gene is part of the solute carrier family, which is a large group of membrane transport proteins that facilitate the movement of a wide variety of solutes across biological membranes. The SLC22A18 protein is thought to play a role in the transport of small molecules.
Clinical significance[edit | edit source]
Mutations in the SLC22A18 gene have been associated with several types of cancer. The gene is located in a region of chromosome 11 that is often deleted in neuroblastoma, lung cancer, and breast cancer. This has led to the suggestion that SLC22A18 may function as a tumor suppressor gene.
Research[edit | edit source]
Research into the SLC22A18 gene and its associated protein is ongoing. Current areas of investigation include the role of the gene in cancer development and progression, and its potential as a target for new cancer therapies.
See also[edit | edit source]
References[edit | edit source]
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