Steatocystoma

Steatocystoma is a rare, benign skin condition characterized by the development of multiple, slow-growing, epidermal cysts. These cysts are filled with sebum, a yellowish, oily substance that helps to lubricate the hair, skin, and nails. Steatocystoma is also known as Steatocystoma Multiplex when multiple cysts are present.

Etiology[edit | edit source]

Steatocystoma is caused by a mutation in the KRT17 gene, which provides instructions for making a protein called keratin 17. This protein is a part of the keratin family, which is a group of tough, fibrous proteins that form the structural framework of certain cells, particularly cells that make up the skin, hair, and nails.

Symptoms[edit | edit source]

The primary symptom of Steatocystoma is the presence of small, smooth cysts on the skin. These cysts are typically skin-colored or slightly yellowish and can appear anywhere on the body, although they are most commonly found on the chest, upper arms, and thighs. The cysts are usually painless, but they can become inflamed and tender if they become infected.

Diagnosis[edit | edit source]

Diagnosis of Steatocystoma is typically made through a physical examination and a review of the patient's medical history. In some cases, a skin biopsy may be performed to confirm the diagnosis.

Treatment[edit | edit source]

Treatment for Steatocystoma typically involves the surgical removal of the cysts. This can be done through a variety of methods, including simple excision, laser therapy, or cryotherapy. In some cases, oral retinoids may be used to reduce the size and number of cysts.