Substance-related disorders

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Substance-related disorders encompass a range of mental health conditions that are characterized by a problematic pattern of using psychoactive substances leading to clinically significant impairment or distress. These disorders are complex and multifaceted, often involving a combination of genetic, psychological, and environmental factors. Substance-related disorders can be broadly categorized into two groups: substance use disorders and substance-induced disorders.

Substance Use Disorders[edit | edit source]

Substance use disorders occur when the recurrent use of alcohol and/or drugs causes clinically and functionally significant impairment, such as health problems, disability, and failure to meet major responsibilities at work, school, or home. According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), the diagnosis of a substance use disorder is based on evidence of impaired control, social impairment, risky use, and pharmacological criteria.

Types of Substances[edit | edit source]

Common substances associated with use disorders include:

Substance-Induced Disorders[edit | edit source]

Substance-induced disorders include conditions such as intoxication, withdrawal, and other substance/medication-induced mental disorders, such as hallucinations or delirium, that are directly attributable to the use of a substance. These disorders can occur in the context of any substance use disorder or independently during or shortly after exposure to a substance.

Intoxication and Withdrawal[edit | edit source]

  • Intoxication is characterized by reversible substance-specific syndrome due to the recent ingestion of a substance.
  • Withdrawal is a substance-specific problematic behavioral change, with physiological and cognitive connotations, that results from the cessation of, or reduction in, heavy and prolonged substance use.

Treatment and Management[edit | edit source]

Treatment of substance-related disorders may involve a combination of medication, counseling, and support groups. The specific approach depends on the type of substance involved and the needs of the individual.

Epidemiology[edit | edit source]

Substance-related disorders affect millions of individuals worldwide, with significant variation in prevalence among different substances and across different regions. The global burden of disease related to these disorders is substantial, contributing to morbidity, mortality, and economic costs.

Prevention[edit | edit source]

Preventive measures for substance-related disorders include policies and programs to reduce the availability of psychoactive substances, education and awareness campaigns aimed at preventing substance abuse, and early intervention programs for those at risk.

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD