Trombosis

From WikiMD's Food, Medicine & Wellness Encyclopedia

Trombosis (commonly referred to as thrombosis) is a medical condition characterized by the formation of a blood clot within a blood vessel, obstructing the flow of blood through the circulatory system. It can occur in any part of the body but is most commonly seen in the legs, a condition known as deep vein thrombosis (DVT). Thrombosis can lead to serious health complications, including pulmonary embolism, stroke, and heart attack, if not promptly diagnosed and treated.

Causes[edit | edit source]

Thrombosis is caused by several factors, often described by Virchow's triad: damage to the vessel wall, alterations in normal blood flow, and changes in the blood's composition. These factors can be triggered by a variety of conditions, including prolonged immobility, surgery, certain medications, smoking, obesity, pregnancy, and genetic predispositions.

Types[edit | edit source]

There are two main types of thrombosis:

  • Venous Thrombosis: Occurs in the veins, with deep vein thrombosis being the most common form. It is primarily associated with slow or stagnant blood flow and can lead to pulmonary embolism if a clot breaks loose and travels to the lungs.
  • Arterial Thrombosis: Occurs in the arteries and is often associated with atherosclerosis. Arterial clots can lead to acute events such as heart attacks and strokes due to the obstruction of blood flow to vital organs.

Symptoms[edit | edit source]

Symptoms of thrombosis depend on the location of the clot but may include swelling, pain, redness, and warmth in the affected area. In cases of arterial thrombosis, symptoms can also include the sudden onset of weakness, paralysis, or speech difficulties, indicating a possible stroke.

Diagnosis[edit | edit source]

Diagnosis of thrombosis typically involves a combination of medical history, physical examination, and diagnostic tests. These tests may include ultrasound imaging, blood tests, and in some cases, more advanced imaging techniques such as MRI or CT scans.

Treatment[edit | edit source]

Treatment for thrombosis aims to prevent the clot from growing and to reduce the risk of further clots. Common treatments include anticoagulant medications, thrombolytic therapy to dissolve clots, and in some cases, surgical intervention. Lifestyle changes and compression stockings are often recommended for those at risk of venous thrombosis.

Prevention[edit | edit source]

Preventive measures for thrombosis include maintaining a healthy lifestyle, avoiding prolonged immobility, and managing risk factors such as high blood pressure and diabetes. For individuals at high risk, doctors may prescribe anticoagulant medication as a preventive measure.


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Contributors: Prab R. Tumpati, MD