UniGene

From WikiMD's Food, Medicine & Wellness Encyclopedia

UniGene is a database that is maintained by the National Center for Biotechnology Information (NCBI). It provides an organized view of the transcriptome, and for each known gene, it presents the sequences that represent the gene's transcriptional landscape.

Overview[edit | edit source]

The UniGene database is a system for partitioning transcript sequences into a non-redundant set of gene-oriented clusters. Each UniGene cluster contains sequences that represent a unique gene, as well as related information such as the tissue types in which the gene has been expressed and map location.

Construction[edit | edit source]

The UniGene database is constructed by partitioning GenBank sequences into a non-redundant set of gene-oriented clusters. Each UniGene cluster contains sequences that represent a unique gene. The process of creating a UniGene cluster involves several steps:

  1. Sequences are partitioned into clusters based on their overlap.
  2. Each cluster is then analyzed to identify the most likely representative sequence.
  3. The representative sequence is then used to search the rest of the database to find other sequences that may belong to the same gene.

Applications[edit | edit source]

UniGene is a valuable resource for many areas of genomic research. These include:

  1. Gene discovery and annotation
  2. Gene expression studies
  3. Comparative genomics
  4. Molecular evolution studies
  5. Disease research

See also[edit | edit source]

References[edit | edit source]


Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD