Virulence
Virilization[edit | edit source]
Virilization is a medical term describing the development of male physical and physiological characteristics in an individual, usually a woman, who typically shouldn't exhibit them. This condition is most commonly the result of an excess of male sex hormones, particularly testosterone.
Causes of Virilization[edit | edit source]
The onset of virilization might be due to a variety of factors, though they predominantly stem from conditions or situations leading to an overproduction or exposure to androgens:
- Ovarian Tumors: Some tumors can produce androgens, leading to virilization.
- Adrenal Tumors: Tumors of the adrenal gland can also produce excessive androgens.
- Polycystic Ovary Syndrome (PCOS): This common condition can lead to elevated androgen levels.
- Congenital Adrenal Hyperplasia: A genetic disorder resulting in altered hormone production.
- Exogenous Androgens: The intake of anabolic steroids or medications containing male hormones.
Signs and Symptoms[edit | edit source]
While the specific manifestations can vary, common signs of virilization include:
- Deepening of the voice.
- Increased body and facial hair (hirsutism).
- Enlarged clitoris.
- Male-pattern baldness or hair thinning.
- Increased muscle mass.
- Changes in body shape towards a more male-like physique.
- Menstrual irregularities or cessation.
Diagnosis[edit | edit source]
If virilization is suspected, a thorough evaluation is necessary:
- Medical History: To understand the onset and progression of symptoms.
- Physical Examination: To assess the extent of masculinization.
- Laboratory Tests: Blood tests to measure hormone levels.
- Imaging Studies: Ultrasound, CT, or MRI to identify tumors or cysts in the ovaries or adrenal glands.
Treatment[edit | edit source]
The approach to treating virilization largely depends on its cause:
- Surgical removal of tumors producing excessive androgens.
- Medications to suppress androgen production or block their effects.
- Hormone therapy, especially in congenital adrenal hyperplasia.
Treatment can reverse some symptoms, but others, like voice deepening, might be permanent.
See Also[edit | edit source]
References[edit | edit source]
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