Whole genome shotgun sequencing

From WikiMD's Food, Medicine & Wellness Encyclopedia

Whole genome shotgun sequencing - a dna sequencing method, which involves random sequencing of tiny cloned pieces of the genome, with no foreknowledge of where on a chromosome the piece originally came from. The sequences obtained have a considerable overlap and by using appropriate computer software it is possible to compare sequences and align them to build larger units of genetic information. This sequencing strategy can be automated and leads to rapid sequencing information.

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Whole genome shotgun sequencing for any updates.



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