4-MeO-PCP

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4-MeO-PCP




4-MeO-PCP (4-Methoxyphencyclidine) is a dissociative anesthetic drug that is chemically related to phencyclidine (PCP). It is known for its hallucinogenic and dissociative effects, which are similar to those of PCP and ketamine.

Chemical Structure and Properties[edit | edit source]

4-MeO-PCP is a member of the arylcyclohexylamine class of chemicals. Its chemical structure consists of a cyclohexane ring bound to a piperidine ring and a methoxy group attached to the phenyl ring. The IUPAC name for 4-MeO-PCP is 1-[1-(4-methoxyphenyl)cyclohexyl]piperidine.

Pharmacology[edit | edit source]

4-MeO-PCP acts primarily as an NMDA receptor antagonist, which is responsible for its dissociative and anesthetic effects. By inhibiting the action of the N-methyl-D-aspartate receptor, it disrupts the normal functioning of the glutamate neurotransmitter system, leading to altered perceptions of reality and consciousness.

Effects[edit | edit source]

The effects of 4-MeO-PCP can vary depending on the dose and individual sensitivity. Common effects include:

  • Dissociation
  • Hallucinations
  • Euphoria
  • Analgesia
  • Altered sensory perception

Legal Status[edit | edit source]

The legal status of 4-MeO-PCP varies by country. In some jurisdictions, it is classified as a controlled substance, while in others, it may be legal or unregulated. It is important to check local laws and regulations regarding the possession and use of 4-MeO-PCP.

Related Compounds[edit | edit source]

4-MeO-PCP is related to several other dissociative anesthetics, including:

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD