5-MAPB

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5-MAPB (5-(2-Methylaminopropyl)benzofuran) is a chemical compound that is structurally related to MDMA and 5-APB. It is a member of the benzofuran class of compounds and is known for its psychoactive effects.

Chemical Properties[edit | edit source]

5-MAPB has a molecular formula of C12H15NO and a molecular weight of 189.25 g/mol. The structure of 5-MAPB includes a benzofuran ring substituted with a methylamino group at the 2-position of the propyl chain.

Pharmacology[edit | edit source]

5-MAPB acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA). It increases the levels of the neurotransmitters serotonin, norepinephrine, and dopamine in the brain, leading to its stimulant and empathogenic effects. The compound is known to produce effects similar to those of MDMA, including euphoria, increased sociability, and enhanced sensory perception.

Usage[edit | edit source]

5-MAPB is primarily used in research settings to study its effects on the central nervous system. It has also been used recreationally, although its legal status varies by country.

Legal Status[edit | edit source]

The legal status of 5-MAPB varies globally. In some countries, it is classified as a controlled substance, while in others, it remains unregulated. Users should be aware of the legal implications of possessing or using 5-MAPB in their respective jurisdictions.

Safety and Toxicity[edit | edit source]

The safety profile of 5-MAPB is not well-documented, and its long-term effects are unknown. As with other research chemicals, caution is advised when handling or using this compound. Potential risks include neurotoxicity, cardiovascular issues, and serotonin syndrome.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD