Androstenediol 17β-acetate

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Androstenediol_17β-acetate.svg

Androstenediol 17β-acetate is a synthetic androgen and anabolic steroid (AAS) and an androgen ester – specifically, the C17β acetate ester of androstenediol. It was never marketed.

Chemical Structure and Properties[edit | edit source]

Androstenediol 17β-acetate is a derivative of androstenediol, which is a naturally occurring androgen and estrogen precursor. The chemical structure of androstenediol 17β-acetate includes an acetate group attached to the 17β-hydroxyl group of the androstenediol molecule. This modification is intended to enhance the pharmacokinetic properties of the compound, such as its bioavailability and half-life.

Pharmacology[edit | edit source]

As an androgen and anabolic steroid, androstenediol 17β-acetate is expected to exhibit similar pharmacological effects to other AAS. These effects include the promotion of muscle growth, increased bone density, and the development of male secondary sexual characteristics. The esterification of the 17β-hydroxyl group is designed to prolong the duration of action of the drug when administered, typically via intramuscular injection.

Clinical Use[edit | edit source]

Androstenediol 17β-acetate was never marketed and thus has no established clinical uses. However, compounds of this nature are generally investigated for their potential in treating conditions such as hypogonadism, muscle wasting, and certain types of anemia.

Side Effects[edit | edit source]

The side effects of androstenediol 17β-acetate would likely be similar to those of other androgens and anabolic steroids. These can include acne, hair loss, gynecomastia, liver toxicity, and cardiovascular issues. Long-term use of AAS can also lead to hormonal imbalances and psychiatric effects.

Legal Status[edit | edit source]

The legal status of androstenediol 17β-acetate varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and adverse health effects.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD