Daledalin

== Daledalin ==

Daledalin is a pharmaceutical drug used primarily in the treatment of hypertension and certain types of cardiac arrhythmias. It belongs to the class of calcium channel blockers, which function by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to a decrease in vascular resistance and myocardial contractility.

Mechanism of Action

Daledalin works by blocking the L-type calcium channels in the cell membrane of cardiac muscle and smooth muscle cells. This inhibition prevents calcium ions from entering the cells, which is essential for muscle contraction. As a result, the drug causes vasodilation and reduces the workload on the heart, making it effective in lowering blood pressure and controlling arrhythmias.

Indications

Daledalin is indicated for:

• Hypertension
• Angina pectoris
• Certain types of cardiac arrhythmias, such as supraventricular tachycardia

Side Effects

Common side effects of Daledalin include:

• Dizziness
• Headache
• Flushing
• Peripheral edema
• Constipation

Serious side effects may include:

• Severe hypotension
• Bradycardia
• Heart failure

Contraindications

Daledalin is contraindicated in patients with:

• Severe hypotension
• Cardiogenic shock
• Severe aortic stenosis
• Known hypersensitivity to the drug

Drug Interactions

Daledalin may interact with other medications, including:

• Beta-blockers
• Digoxin
• CYP3A4 inhibitors
• Grapefruit juice

Dosage and Administration

The dosage of Daledalin varies depending on the condition being treated and the patient's response to the medication. It is typically administered orally, with or without food. Dosage adjustments may be necessary for patients with renal impairment or hepatic impairment.

Monitoring

Patients on Daledalin should be regularly monitored for:

• Blood pressure
• Heart rate
• Signs of heart failure
• Electrolyte levels

See Also

• Calcium channel blocker
• Hypertension
• Cardiac arrhythmia
• Angina pectoris

External Links

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