Fluazacort

Fluazacort.svg

Fluazacort is a glucocorticoid used in the treatment of various inflammatory and autoimmune conditions. It is a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties.

Pharmacology

Fluazacort works by inhibiting the release of substances in the body that cause inflammation. It is similar to other corticosteroids like prednisone and dexamethasone, but it has a unique chemical structure that may offer different pharmacokinetic properties.

Medical Uses

Fluazacort is used to treat a variety of conditions, including:

• Rheumatoid arthritis
• Asthma
• Allergic reactions
• Inflammatory bowel disease
• Lupus erythematosus

Mechanism of Action

Fluazacort binds to the glucocorticoid receptor in the cytoplasm of cells. This complex then translocates to the cell nucleus, where it binds to glucocorticoid response elements in the DNA, modulating the transcription of various genes involved in inflammatory and immune responses.

Side Effects

Common side effects of fluazacort include:

• Weight gain
• Hypertension
• Hyperglycemia
• Osteoporosis
• Increased risk of infection

Contraindications

Fluazacort should not be used in patients with:

• Systemic fungal infections
• Known hypersensitivity to the drug

Dosage and Administration

The dosage of fluazacort varies depending on the condition being treated and the patient's response to therapy. It is typically administered orally, but the exact regimen should be determined by a healthcare provider.

See Also

• Corticosteroid
• Anti-inflammatory
• Immunosuppressive drug

External Links

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